Welcome to the Russ Lab

Advancing research in autoimmune Type 1 Diabetes through innovative stem cell and regenerative medicine approaches at the University of Florida Diabetes Institute (UFDI).

Our Mission

The goal of the Russ Lab is to work towards the betterment of human health with a focus on autoimmune type 1 diabetes. We test innovative hypotheses through rigorous scientific inquiry to expand scientific knowledge and improve experimental approaches.

About Us

The Russ Lab focuses on developing innovative regenerative medicine approaches to understand the molecular and cellular mechanisms behind autoimmune Type 1 Diabetes (T1D).
We utilize human pluripotent stem cell technology, primary human tissue culture, and genome engineering to model disease and explore treatment possibilities.
Our work contributes to pancreatic beta-cell biology, thymus research, and stem cell science. Our long-term goal is to understand T1D development, create new treatment strategies, and train the next generation of scientists.

Research Interests

Cell Replacement

Cell Replacement Therapy

We explore stem cell-derived organoids to develop curative treatment options for Type 1 Diabetes.
Human Cell

Human Beta Cell Biology

We study beta cell function, drug testing, and T-cell interactions to understand disease progression.
Human Thymus

Human Thymus Research

We develop thymic organoids to study immune system behavior and autoimmune disease mechanisms.

Leadership

Holger

Holger Russ, PhD

Primary Investigator

Post Doctoral Fellows

Jessie

Jessie Barra, PhD

Post Doctoral Fellow

Adrienne

Adrienne Widener, PhD

Post Doctoral Fellow

Students

Austin

Austin Kratz, MS

4th year PhD candidate

"Alexander Baker "

Alexander Baker, BS

3rd year PhD candidate

Matthew

Matthew Brown, BS

MD/PhD student

Jade

Jade Nguyen, BS

2nd year PhD student

Staff

Andrew

Andrew M. Ladd, MS

Lab Manager

Zach

Zack Numark, BS

Lab Tech

Undergraduates

Alumni

UF Diabetes Institute

The Russ Lab is a part of the Diabetes Institute here at the University of Florida. Here we join forces with Physicians and researchers to try to treat and discover cures for autoimmune Diabetes, we also share space with nPOD, the leading pancreatic organ donation network for research, an invaluable resource to us and the Diabetes world

Useful Resources

📍 Location:

Biomedical Sciences Building
University of Florida

Address:

1275 Center Drive, Gainesville, FL 32610

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